Quantitative DIC

The program is used to integrate the quantitative differential interference contrast microscopy (qDIC) images. It reads raw DIC images and performs DIC inverse transformation using the Wiener deconvolution principle, and saves the differential phase delta and integrated phase phi as tiff, ascii and matlab binary files.

If you use the software for publications, please give credit and cite some of our related publications.

Publications

• Quantitative measurement of graphitic sp² on single nanodiamonds with sub-monolayer sensitivity using differential interference contrast and photo-thermal microscopy
  S. Hamilton, D. Regan, L. Payne, P. Borri, W. Langbein
  Carbon 228, 119371 (2024) DOI 10.1016/j.carbon.2024.119371
• Optical absorption and dichroism of single melanin nanoparticles
  D. Regan, A. Mavridi-Printezi, M. Montalti, L. Payne, P. Borri, W. Langbein
  Analyst 148, 3531 (2023) DOI 10.1039/d3an00654a
• Sizing individual dielectric nanoparticles with quantitative differential interference contrast microscopy
  S. Hamilton, D. Regan, L. Payne, W. Langbein, P. Borri
  arXiv 2111.07186; Analyst 147, 1567 (2022) DOI 10.1039/d1an02009a
• Lipid bilayer thickness measured by quantitative DIC reveals phase transitions and effects of substrate hydrophilicity
  D. Regan, J. Williams, P. Borri, and W. Langbein
  Langmuir 35, 13805 (2019) DOI 10.1021/acs.langmuir.9b02538
• Measuring sub-nanometre thickness changes during phase transitions of supported lipid bilayers with quantitative differential interference contrast microscopy
  D. Regan, J. Williams, F. Masia, P. Borri, and W. Langbein
  SPIE BIOS, 2-7 February 2019, San Francisco, USA; Proc. SPIE 10887, Quantitative Phase Imaging V, 1088719 (2019) DOI 10.1117/12.2510461
• Coherent anti-Stokes Raman scattering microscopy of single nanodiamonds
  I. Pope, L. Payne, G. Zoriniants, E. Thomas, O. Williams, P. Watson, W. Langbein, P. Borri
  Nature Nanotechnology 9, 940946 (2014) DOI 10.1038/NNANO.2014.210
  
• Measuring the Lamellarity of Giant Lipid Vesicles with Differential Interference Contrast Microscopy
  Craig I. McPhee, George Zoriniants, Wolfgang Langbein, and Paola Borri
  Biophysics J. 105, 1414 (2013) DOI 10.1016/j.bpj.2013.07.048

Program versions

• Version 2.22
  
• Version 3.20